My research applies exposomic approaches to investigate the influence of environmental factors on disease. Robust, reliable, reproducible, and rigorous analytical and computational techniques are required to operationalise the exposome framework for application in population studies. My work has focused on addressing the technical hurdles of performing systematic and comprehensive measurements of environmental chemicals using high resolution mass spectrometry. My research team has pioneered technologies for exposomics, including a wearable passive sampler (Fresh Air wristband) to assess personal exposure to thousands of contaminants in the environment, including pesticides and phthalates, and software for non-targeted analysis (FluoroMatch) to expand coverage of emerging chemicals in environmental and biological matrices.